Membrane Protein Reagents for Research & Drug Discovery
Call Us: 408-758-8654

Site-Directed Mutagenesis Service


Our Site-Directed Mutagenesis (SDM) services include PCR based SDM for plasmids <10 kb, Quikchange mutagenesis for plasmids >10 kb, or by using synthetic fragments.   Although we use the highest fidelity DNA polymerase currently available to limit spurious errors, we can also transfer the mutagenized gene into a “fresh” vector if desired.

  • Nucleotide Substitutions

  • Insertions

  • Deletions

Simply provide us with your plasmid, nucleotide sequence (text file) and mutagenesis requirements.  We will provide confirmation sequencing and ~4 ug of the final plasmid upon completion.


Telephone:  408-758-8654